Medical and Health Science Journal
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| Volume | 3 |
| Issue | 3 |
| Online publication date | 2010-09-15 |
| Title | Regulation of homeostasis in the process of protein absorption from small intestine to blood |
| Author | Gulnara Islamova, Aziza Nishanova, Margarita Tarinova, Mukaddas Rahmatova, Akmal Yuldashev |
| Abstract | Electron microscopic and immunоfluorescent study in rats aged 1 and 3 days after birth allowed to establish a process of absorption of protein from the small intestine into the lymph and blood. Blood homeostasis was provided by the proteins filtrated from glomerular capillaries of nephrons and reabsorbed by the epithelial cells in canaliculi of nephrons. The absorbed natural heterologous protein was depleted by lysosomes of epithelial cells of intestine and kidneys and macrophages. It supported not only blood homeostasis but also prevented loss of protein by an organism, formed sites for its digestion in the organism. |
| References | Allan, V., Thomson, H., McNiven, M., 2004. “Motoring around the Golgi,” Nature Cell Biol., 4, pp.E236-E242. Burmakin, M., Seliverstova, E., Natochin, Y., 2005. “Accumulation of yellow flourescent protein in kidneys after its absorption in the intestine of rats,” M. Sechenov Journal of Rus. Physiol., No4, pp.1195-204. Leibach, F., Ganapathy, V., 1996. “Peptide transporters in the intestine and the kidney,”Ann.Rev.Nutr., Vol.1, рр.99-119 Luft, V., 2003. “Theoretical and practical trophology,” Russian Journal of Gastroenterology, Hepatol, Proctol. 14 (14) Supllement 20 , pp.13-16 Panina, V., Rumyantsev, A., Menshutina, M. et al., 2007. “Specific functions of endothelium at chronic kidney diseases,” Nephrology, No4, pp.28-46 Remuzzi, D., Bertani, T., 1999. “Pathophysiology of progressing nephropathia,” International Journal of Medicine, 1-2, pp.78-85 Rothman, J., Wieland, F., 1996. “Protein sorting by transport vesicles,”Science, 272: рр.227-34 Seliverstova, E., Burmakin, M., Shakhmatova, E. et al., 2007. “Accumulation of the exogenous protein being absorbed by intestine in the kidneys of rats after the experimentally induced chromic renal insufficiency,” Nephrology, No1, pp.7-16 Snigirevskaya, E., Sokolova, Y., Kommissarchik, Y., 2006. “Structural-functional organization of Golgi apparatus,” Gysologia. 48:1; рр.57-81 Titov, V., 2007. “Biologic ‘litter’ utilization activated with angiotensin II in tunica intima of arteries after inducing endogenic inflammation,” Clin.Lab.Diagnostics, No5, pp.3-12 Yuldashev, A et al., 2009a. “Regulation of homeostasis in small intestine and mechanisms of development of polyorganic pathology at its disorders,” Med. Journal of Uzbekistan, No1, pp.66-69 Yuldashev, A. et al., 2009b. Mechanisms of homeostasis regulation in the process of transition of the proteins absorbed in small intestine into blood vessels,” Med. Journal of Uzbekistan, No5, pp.79-87 Zufarov, K., Yuldashev, A., 1999. “Small intestine: Development, maturation, aging,” Med. Journal of Uzbekistan, No4, pp.9-16 Zufarov, K., Yuldashev, A., 2001. “Small Intestine,” in: Handbook on histology, St. Petersburg, Vol.2, pp.115-40 |
| Keywords | Small intestine, kidney, protein, absorption, reabsorption, homeostasis |
| Pages | 9-13 |
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