Medical and Health Science Journal
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| Volume | 6 |
| Issue | 2 |
| Online publication date | 2011-04-04 |
| Title | Some immunological changes in inbred children with frequent illness |
| Author | Shaanvar Shamansurov, Durdona Gulaymova, Nodira Abdushukurova, Nariman Gulyamov, Khalida Akhmedova |
| Abstract | The parameters of cellular immunity were studied in 17 children before and one month after treatment. The analysis of parameters of the cellular immunity (CD3 , CD20 , CD4 and CD8 regulatory subpopulations of Т-lymphocytes) showed that they are within the limits of the standard norms both in the group of healthy children from inbreeding marriage and in group of relatively healthy ones from non-inbreeding marriage. However, in the sick children from inbreeding marriage the diseases induced more profound immune deficiency; and the consequence of that is less expressed effect from performed specific neurological treatment in these patients. |
| References | Garib F., Gurariy, N., Afanasiev, Yu., 1983. Clinical value of determination of antigen-binding lymphocytes at the patients with typhoid fever and other diseases [Klinicheskaya cennost opredeleniya antigensvyazivayushtih limfocitov u bolnih bruyshnim tifom i drugimi zabolevaniyami], in Russian, Methodical recommendations, Tashkent Garib, F., Gurariy, N., Garib, V. et al., 1995. “Method of determination of lymphocyte subpopulation,” Official Bulletin [Rasmiy ahborotnoma], in Uzbek, Tashkent, No.1, p.90 Garib, F., Zalyalieva, M., 1989. Methods of study of lymphocyte subpopulations in human under pathological condition [Metodi izucheniya subpopulyaciy limfocitov u cheloveka pri patologicheskih sostoyaniyah], in Russian, Methodical recommendations, Tashkent Gulamov, N., Akhmedova, Kh., Dalimov, T., Imamova, I., Yuldasheva, F., 2005. “Diagnostic significance of antigen-binding lymphocyte parameters in the estimation of organ impairment in infectious and non infectious pathology,” Infection, Immunity and Farmacology [Jurnal Infeccia, immunitet i farmakologia], in Russian, No.3, pp.115-18 Gulamov, N., Akhmedova, M, Akhmedova, Kh., Mirzaeva, U., 2002. “Variants and clinical estimation of secondary immune deficits in intestinal,” Bulletin of Practioning Doctor [Bulletin Practicheskogo Vracha), in Russian, Samarkand, No.2, pp.22-24 Khaitov, R., Pinegin, B., 2000. “The current understanding about body defense system from infection,” Immunology [Immunologia], in Russian, No.1, pp.61-64 |
| Keywords | Inbreeding, immunological changes, antigen-binding lymphocytes |
| Pages | 12-16 |
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