Chemistry of Heterocyclic Compounds

Sample articles
Chemistry of Heterocyclic Compounds Chemistry of Heterocyclic Compounds publishes articles on the synthesis, structure, reactivity, and biological activity of heterocyclic compounds including natural products ISSN: 1573-8353 (ONLINE) ISSN: 0009-3122 (PRINT) Journal metadata

Sample articles
  • Publisher

    Springer-Verlag GmbH
    Inga Schildmann

    Tiergartenstr. 17 
    69121 Heidelberg 

  • Aims and scope

    Chemistry of Heterocyclic Compounds publishes articles, letters to the Editor, reviews, and minireviews on the synthesis, structure, reactivity, and biological activity of heterocyclic compounds including natural products. The journal covers investigations in heterocyclic chemistry taking place in scientific centers of all over the world, including extensively the scientific institutions in Russia, Ukraine, Latvia, Lithuania and Belarus.

    Chemistry of Heterocyclic Compounds is a translation of the peer-reviewed Russian language journal Khimiya Geterotsiklicheskikh Soedinenii.

    The Russian Volume Year is published in English from April.
    All articles are peer reviewed.

  • Indexing


    Academic OneFile, Academic Search, AGRICOLA, Chemical Abstracts Service (CAS), Chemistry Citation Index, ChemWeb, Chimica, Current Abstracts, Current Chemical Reactions, Current Contents/Physical, Chemical and Earth Sciences, EBSCO, Gale, Google Scholar, Index Chemicus, Journal Citation Reports/Science Edition, Mass Spectrometry Bulletin, OCLC, Reaction Citation Index, Reaxys, Science Citation Index, Science Citation Index Expanded (SciSearch), SCOPUS, Summon by Serial Solutions

  • Editors

    Editor-in-Chief I. Kalvinsh (Latvia)

    Deputy  Editior and Regional Editor: L. I. Belen'kii (Russia)
    Regional Editor: M. A. Yurovskaya (Russia)

    Managing Editor: I. Jaunzeme (Latvia)
    Production Editors: A. Amoliņš (Latvia)
    Publishing Editor: A. Skorova  (Latvia)
    Advisory Board:
    O. N. Chupakhin  (Russia), G. Duburs (Latvia), A. R. Katritzky (USA), M. Makosza (Poland)
    V. I. Minkin (Russia), H. van der Plas (Netherlands),  A. F. Pozharskii (Russia)
    F. Sauter (Austria), V. Snieckus (Canada), J. Stradins (Latvia), B. A. Trofimov (Russia)
    R. Valters (Latvia), E. Vedejs (USA), M. G. Voronkov (Russia), N. S. Zefirov (Russia)

    Editorial Board:
    E. V.  Babaev (Russia), A. Barański (Poland), A. V. Butin (Russia), G. G. Danagulyan (Armenia)
    V. Gevorgyan (USA), A. V. Gulevskaya (Russia), V. G. Kartsev (Russia)
    V. A. Kovtunenko (Ukraine), R. G. Kostyanovsky (Russia), M. A. Kuznetsov (Russia)
    E. Liepinsh (Latvia), V. A. Ostrovskii (Russia), Yu. G. Shermolovych (Ukraine)
    A. A. Tolmachev (Ukraine), S. Tumkevicius (Lithuania), I. V. Ukrainets (Ukraine)
    A. V. Varlamov (Russia), A. Zicmanis (Latvia)

  • Guide to authors

    1. General Statement

    1.1. The Journal “Chemistry of Heterocyclic Compounds” publishes original papers, letters to the Editor, reviews, and minireviews dealing with the problems of heterocyclic chemistry in Russian and English. The Journal also publishes reviews and annotations on new books, as well as brief reports on scientific congresses, symposia, conferences, etc. in the field of heterocyclic chemistry, the materials dedicated to chemists-heterocyclists.
    The manuscript should be concisely written, thoroughly drawn up, and edited. It should be easy to understand, and the results should be reproducible.

    1.2. Original papers may concern synthesis, structure, reactions, and properties of heterocyclic compounds, as well as their pharmacological properties. Transformations of substituents in a heterocycle may be considered when their character is specific, due to a special effect of the heterocyclic system. The author is fully responsible for the reliability of experimental data presented in his paper. Original papers should not exceed 10–15 journal pages.

    1.3. Letters to the Editor should contain substantially new results or methods of wide applicability or interest, or focused studies of general interest requiring establishment and fixation of their priority. Only those experimental data and literature references should be presented which are necessary for confirmation of the main conclusion. Letters to the Editor should not exceed 3 journal pages.

    1.4. The topic of a review or minireview should be submitted preliminarily for the approval by the Editors in the form of a detailed (1–2 pages) annotation.
    Reviews or minireviews should cover the topics that present sufficiently general interest for heterocyclic chemistry or reflect an important aspect of practical application of heterocyclic compounds in industry, agriculture, medicine, etc.
    Reviews should be comprehensive, critical, and readable contributions of recent research in heterocyclic chemistry. The time period and the scope of the subject area should be clearly defined in the introduction. Review manuscripts should not exceed 35 journal pages and minireviews – 15 journal pages.

    2. Manuscript Evaluation

    All manuscripts will be reviewed by two or more referees. Authors can suggest two referees. Referees evaluate manuscripts on their significance, scientific rigor, originality, breadth of interest to the heterocyclic chemistry community, thoroughness of compound characterization, appropriateness of cited literature, and quality of writing.
    The evaluation process is confidential. An exception is possible only in the case when a referee alleges an intentional presentation of false data in the manuscript. The authors are given a possibility to see the reviews of their manuscript.
    The Editors take the final decision about the compliance of each submitted manuscript to the Journal guidelines.
    At the time the manuscript is submitted to the Journal, and during the evaluation, no other manuscript reporting the same results may be submitted to another journal.

    3. Manuscript Organization

    3.1. The text of the manuscript of an original article or a review must begin with the authors’ initials and names.
    In a letter to the Editor, the authors' initials and names are placed after the reference list. The name of the corresponding author(s) should be marked with an asterisk (*). If the co-authors are not from one institution or department, the institutional affiliation of each author should be indicated after the name by labeling with a lower case superscript letter.
    Example: A. S. Alekseyev*, G. I. Popova, I. V. Ivanovab.

    3.2. The title of the paper should provide maximum information fully disclosing the essence of the work. Abbreviations should be avoided.
    When a publication is a serial communication, a footnote is added (to the number of communication) referring to the preceding paper. Serial communications are numbered with Arabic numerals. If the topic of the series does not correspond to the Journal profile, its title should be given in a footnote, e.g., "Communication 9, series "Quinones"; for communication 8 see [1]."

    3.3. The title of the paper should be followed by a brief abstract where the purpose of the research, the main results, and the major conclusions of the study should be stated. The abstract should not contain codes of the compounds, experimental details, and reference citation numbers. Letters to the Editor require no abstracts.

    3.4. Then keywords are given (5–10) reflecting the general type of the compounds under investigation and the character of the reactions.

    3.5. In the initial paragraph of the main text a brief discussion of the available literature on the present research topic should be given followed by a clear explanation of the purpose and objectives of the research done by the authors.
    Afterwards, all significant results should be discussed. Experimental details should be kept to a minimum. Reiteration of information from tables, figures, and schemes should be avoided. Only those spectral data should be mentioned and discussed which are essential to confirm the structure of the synthesized compounds. All tables should have a title, and all figures should be supplied with captions that do not duplicate the main text. The number of figures should be kept to minimum. The main text ends with a brief conclusions section about the performed research.

    3.6. At the beginnig of the experimental section the instruments should be named that were used to characterize the synthesized compounds. The sources of all non-trivial reagents, their commercial source or literature references for their synthesis should be given. Each paragraph describing a synthetic experiment should start with the product’s systematic (IUPAC) name and the structure number assigned to the compound in the discussion section. For all new compounds, evidence sufficient to establish both the identity and degree of purity (homogeneity) must be provided. In particular, the elemental analysis results or high-resolution mass spectra data should be provided, as well as 1H (and 13C, if necessary) NMR spectra. For the known compounds synthesized following a published procedure a reference should be given. For the known compounds synthesized by a new or modified procedure physical characteristics and spectral data should be given with the data from the literature for comparison, and the reference. Sections 4.6., 4.7, and 4.8. should be used for guidance on reporting the experimental procedure, compound characterization, spectroscopic, crystallographic, and computational data.
    If, in the opinion of the Editor, new compounds have not been satisfactorily characterized, the paper will not be accepted.

    3.7. The main text of the paper ends with a list of references. The references should be numbered with Arabic numerals in the order of their first citation in the text, and the corresponding citation numbers should be inserted at the appropriate locations in the text in the square brackets. Only one source should be noted under one reference number. The conventional abbreviations for the titles of the journals and handbooks should correspond to those used in Chemical Abstracts. The references to unpublished results or private communications may be given only as footnotes; they should not be numbered or included in the reference list. The only exceptions are papers previously sent by the authors to Khimiya Geterotsiklicheskikh Soedinenii (Chemistry of Heterocyclic Compounds) but yet not published. These may be included in the reference list with full title of the paper mentioned.

    3.8. At the end, the full name(s) of institution(s) where the work was performed and their location(s), including street or P.O. box number, city, postal code, and country, should be given. The address line should be followed by the email address of the corresponding author.

    3.9. For each manuscript, a graphical abstract should be supplied in a separate file complete with the authors' initials
    and names, the title of the article and a graphic in the form of a structure or reaction equation. The graphical abstract in connection with the title should attract the readers' attention and give a visual representation of the article's content.

    4. Manuscript Presentation Requirements

    4.1. Manuscripts must be prepared using MS Word and sent to the Editorial office e-mail as a doc and pdf file. To properly format the manuscript, the template should be used.

    All pages of the manuscript including a list of references, tables, and figure captions should be numbered. Equations, schemes, tables, and figures must be numbered strictly in the order of their mentioning in the text.

    4.2. Common abbreviations, acronyms, and symbols may be used, but less common ones should be defined the first time they are used. The dimension of the units is given in accordance with the international system of units. The symbols used for physical constants should be in italics (e.g. d, J, k, c, m/z), but the respective units of measurement should
    not be italicized. Abbreviations of words secondary and tertiary, as well as abbreviations of prefixes ortho-, meta-, para-, etc. should be written in formulas with Roman letters: as s-, t-, o-, m-, p-, i-, cis-, trans-.

    4.3. Chemical structures should be written using ISIS Draw (Symyx Draw): font Times New Roman, size 9 pt, bond length 0.5 cm, in the graphical abstract font size – 7 pt, bond length 0.4 cm. The scheme should not exceed 12.5 cm.
    Cumbersome schemes (12.522.5 or 22.512.5 cm) may be presented on separate sheets. It is desirable to indicate the reaction conditions over the arrow.

    4.4. The figures must be attached by a separate file in jpg format with a minimum resolution of 300 dpi. The size of a figure should allow one to see it in detail (minimum size is 9.0×12.0 cm, maximum size is 12.0×22.5 or 22.512.0 cm).
    Whenever possible, use numbers, instead of labels, to identify items in a figure, and give the corresponding explanation of these numbers in the figure caption. Color figures will not be accepted.

    4.5. It is desirable to use standard abbreviations and unequivocal molecular formulas for reagents and solvents, as well as Arabic numerals for the reactants, intermediates, and products in the order of their first mentioning in the text.
    Compounds of related structure may use a common number, e. g., "RX (2)"; for their derivatives with different substituents a letter is added to the number, e. g., "alcohol X = OH (2a), acetate X = OAc (2b), tosylate = OTs (2c)."
    When the full name of a compound is mentioned its numerical designation is given in parentheses. The codes without a generalizing word should not be used, e.g. "the reaction of compound 2" – not "the reaction of 2". Stereochemical and structural symbols, characterizing structural peculiarities or a substituent position in a molecule, are composed in italics,
    e.g., "(R)-enantiomer," "tert-butyl," "p-xylene", "N-alkyl", pyridin-2(1H)-one. Cumbersome names of simple compounds should be replaced by their chemical formulas, e.g., "NaBr" should be used instead of "sodium bromide".

    4.6. The experimental section should be written in the present tense ("is boiled, dried, etc."). For chemical compounds that are described for the first time, a full name according to IUPAC rules should be given. The quantities of reactants and reagents should be given in both weight and molar units, e.g., "2-ethynylpyridine (0.103 g, 1.0 mmol)". The
    decimal digits in numbers should be separated by the point. Yields should represent weighed amounts of isolated and purified products, and should be reported as mass and as percentage of the theoretical value. In molecular formulas, elements should be arranged according to the Chemical Abstracts system: C, H, and then all other elements in Latin alphabetical order. Formulas of molecular adducts and onium salts are given with raised dots, e.g. “C6H12N2.2HCl”. 
    When flash chromatography is used for product purification, both the support and eluting solvent should be identified.
    It is recommended to present physical constants and spectral characteristics in form of tables. Each table should be
    provided with a descriptive title, above the table. The title, together with the individual column headings, should make the table, as far as possible, self-explanatory. The values mentioned in the tables should be identified in the headings, and a comma is used to separate the quantity from its unit of measure, e.g. "Yield, %". Tables must be created using MS Word
    table format.

    4.10. The list of references should include the initials and names of all authors ("et al." is not allowed). The reference section should be written as follows:

    Books. The page or chapter should be indicated when discussing particular topics.
    A. F. Pozharskii, Theoretical Fundamentals of the Chemistry of Heterocyclic Compounds [in Russian], Khimiya, Moscow, 1985.
    General Organic Chemistry, D. Barton and U. D. Ollis (Eds.), [Russian translation], Khimiya, Moscow, 1985, Vol.9, p.45.
    A. R. Katritzky and A. F. Pozharskii, Handbook of Heterocyclic Chemistry, Pergamon, Amsterdam, etc., 2000.

    Papers in Collections and Handbooks
    A. K. Sarkar, in Rodd’s Chemistry of Carbon Compounds, S. Coffey (Ed.), Elsevier Science Publishers Co, Amsterdam, 1974, Vol. IIIb, p. 236.
    H. Glaser, in Houben-Weil Methoden der Organischen Chemie, Georg Thieme Verlag, Stuttgart, 1957, B. XI, Teil 1, S.108.

    Journals. Only for journals in which each issue begins with page 1 the issue number is included.
    O. Neilands, Khim. Geterotsikl. Soed., 1763 (2003). [Chem. Heterocycl. Comp., 39, 1551 (2003)].
    N. S. Zefirov, Dokl. Akad. Nauk, 252, 111 (1980).
    E. Lukevics, N. P. Erchak, and L. E. Demicheva, Khim.-Farm. Zh., 26, No. 1, 45 (1992).
    F. C. Schaeffer and G. A Peters, J. Org. Chem., 26, 2778 (1961).
    R. Maroni, G. Melloni, and G. Modena, J. Chem. Soc., Perkin Trans. 1, 353 (2001).
    T. Sato, Yakugaku zasshi, 77, 771 (1957); Chem. Abstr., 51, 17941 (1957).

    Author’s Certificates, Patents
    O. E Nasakin, E. G. Nikolaev, USSR Author’s Certif. 1168554; Byul. Izobret., No. 27, 90 (1985) [in Russian].
    J. E. Dunbar and J. W. Zemba, US Pat. Appl. 3764608; hem. bstr., 80, 14852 (1974).
    D. A. Maiboroda, Abstract of Diss. Cand. Sci. (Chem.), Moscow, 1998.
    L. A Rodinovskaya, Thesis Dr. Sci. (Chem.), Moscow, 1994.

    The manuscripts that do not follow the above rules will not be accepted.
    For the preparation of manuscripts and graphical abstracts the templates should be used that are found on the Journal's website:

    5. The Publishing Process

    Manuscripts for publication should be sent by means of electronic mail to or as files named using Roman letters only and allowing easy identification. Names such as article, paper, table, pyridine, stat, hgs should be avoided.
    The authors are asked to send to the Editorial Office the Consent to Publish by mail and a scanned copy by electronic mail. The form of the Consent to Publish can be found on the Journal's website. When the paper is published, the copyright is transferred to the Publisher.
    A separate file should be added that contains information about the corresponding author: business and home address and phone number, fax number, e-mail address.

  • Contact

    Adress of the Editorial Board of the Journal
    "Khimiya Geterotsiklicheskikh Soedinenii"

    Latvian Institute of Organic Synthesis
    Aizkraukles 21, Riga, LV-1006, Latvia
    phone: 371 67555918 / 371 67014921
    fax / phone: 371 7550338

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