Journal of Chemical Biology

Sample articles

• Sample Volume 1

Journal of Chemical Biology publishes original and innovative research as well as topical research summaries of the highest quality catering to both the physical and life sciences ISSN: 1864-6166 (ONLINE) ISSN: 1864-6158 (PRINT) Journal metadata

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• Aims and scope
• Profile
• Editors
• Guide to authors
• Contact
• Call for papers

• Aims and scope

  Chemical Biology is a novel interdisciplinary subject that is still evolving. Interpreting chemical biology as widely as possible, the "Journal of Chemical Biology" (JOCB) will be open towards the whole spectrum of physical sciences research if it is applied to foster biomedical research. This will include innovative theoretical and experimental approaches and tools being applied to elucidate biological problems. Chemical Biology is not a synonym for Biological chemistry/Biochemistry, the latter being served by a plethora of life sciences journals, where well-established tools and techniques drawn from the physical sciences are employed to produce innovative biological research. The main acceptance criteria are therefore: the novelty/innovation in the physical sciences part of the presented interdisciplinary research and/or its application in biological research. Manuscripts are expected to convey their research in a fashion that allows both research communities to appreciate its significance and achievements. Thus, experts drawn from the life as well as the physical sciences background referee all manuscripts.
  
  

  The journal is keen to attract articles on novel innovations and discoveries in the physical sciences that can be applied in the cellular environment (in vivo). Important discoveries that have not yet reached the necessary proof for their biological relevance will be presented as short communications. Reviews and opinion papers as well as articles and short communications that present original multidisciplinary research with a clear applicability towards the life sciences are welcome. JOCB also invites to submit these research advances of interesting tools and technology developmentsthat are not yet applicable towards biological problems as "notes". Being an interdisciplinary journal we would like to encourage reviews on interdisciplinary subjects from authors affiliated with both disciplines as well as investigators affiliated in one discipline with the desire to become engaged in this new interdisciplinary research area.

  
  

  The "Journal of Chemical Biology" endeavors to create a platform for multidisciplinary physical scientists to publish their achievements, retrieve information, and exchange ideas, opinions and thoughts with the biomedical research community. The latter is addressed in the "Journal of Chemical Biology Bulletin", which is published with each issue and will contain information that is relevant for the chemical biology research community. This includes book reviews, meeting reports and announcements as well as information on chemical biology studies and education.

• Profile

  Chemical biology was established initially as an interdisciplinary approach that employed chemical synthesis to address biological questions. However, this research area is now growing and evolving, quickly absorbing more and more aspects of physical sciences (experimental as well as theoretical tools and techniques) that can be used to elucidate research problems in the life sciences (biological and medical). It is our ambition to create a journal that publishes original and innovative research as well as topical research summaries of the highest quality catering to both the physical and life sciences. Prospective manuscripts will therefore need to employ innovative tools and/or techniques drawn from the physical sciences to address biological/medical research problems in a quantitative fashion. The peer-review process will incorporate expertise from both disciplines to ensure that the highest standards are reached.
  
  
  The "Journal of Chemical Biology" (JOCB) will be the platform for this evolving multidisciplinary research community by
  
  
  - disseminating new research achievements through short communications or articles,
  - discussing and creating awareness of research trends through opinion papers and reviews,
  - sharing interesting tools and developments that are not yet applicable towards biological problems as notes,
  - exchanging information within the chemical biology research community, which includes news on conferences, grants, and job opportunities as well as book and instrument reviews.

• Editors

  Editors-in-Chief:
  
  
  Dr. Rudiger Woscholski 
  Div. of Cell and Molecular Biology
  Faculty of Natural Sciences
  and Chemical Biology Centre (CBC)
  Imperial College London
  South Kensington campus
  London, SW7 2AZ, UK
  Tel/fax: 44 (0)20 7594 5305
  r.woscholski@imperial.ac.uk
  http://www.bio.ic.ac.uk/research/woscholski/woscholski.html
  http://www.chemicalbiology.ac.uk/
  
  
  Prof. Banafshe Larijani
  Department of Cell Biophysics
  Cancer Research UK
  44 Lincoln's Inn Fields
  London, WC2A 3PX, UK
  Tel: 44-(0) 20-72693082
  Fax: 44-(0) 20-72693094
  banafshe.larijani@cancer.org.uk
  http://science.cancerresearchuk.org/research/loc/london/lifch/larijanib/
  
  
  
  
  Bulletin Editor:
  
  
  Dr. Colin A. Rosser
  1 North Parade
  Derby
  DE1 3AY
  United Kongdom
  rosserca@hotmail.co.uk
  
  
  
  
  Assistant News Editor:
  
  
  Gary Chung
  Cell Biophysics Laboratory 
  Cancer Research UK
  Lincolns Inn Fields Laboratories
  London Research Institute
  44 Lincoln’s Inn Fields
  London WC2A 3PX.
  UK
  tina.hobday@cancer.org.uk
  
  
  Nirmal Jethwa
  Cell Biophysics Laboratory 
  Cancer Research UK
  Lincolns Inn Fields Laboratories
  London Research Institute
  44 Lincoln’s Inn Fields
  London WC2A 3PX.
  UK
  nirmal.jethwa@cancer.org.uk
  
  
  Advisory Board:
  
  
  Prof. Manfred Auer, PhD
  SULSA Chair of Chemical & Translational Biology
  The University of Edinburgh
  Mayfield Road
  Edinburgh, EH9 3JR, U.K.
  manfred.auer@ed.ac.uk
  
  
  Dr. Weng C Chan
  Centre for Biomolecular Sciences
  School of Pharmacy, 
  University of Nottingham
  University Park
  Nottingham NG7 2RD, U.K.
  weng.chan@nottingham.ac.uk
  
  
  Dr. Ian Collins
  Cancer Research UK Centre for Cancer Therapeutics
  The Institute of Cancer Research
  15 Cotswold Road, Sutton
  Surrey SM2 5NG, U.K.
  ian.collins@icr.ac.uk
  
  
  Dr. Jens R. Coorssen, Ph.D.
  Chair, Molecular Physiology
  UWS School of Medicine
  Campbelltown, NSW, Australia
  Tel: 61 2 9852 4726 
  J.Coorssen@uws.edu.au
  
  
  Dr. Erick J Dufourc
  Directeur
  UMR 5248 CBMN, CNRS-Universite Bordeaux 1-ENITAB
  IECB, 2 rue Robert Escarpit
  33607 Pessac, France
  e.dufourc@iecb.u-bordeaux.fr
  
  
  Dr. Maria M. Flocco
  Senior Director 
  Lead Discovery and Structural Biology & Biophysics
  Pfizer Global Research & Development
  Sandwich, Kent CT13 9NJ, UK
  maria.flocco@pfizer.com
  
  
  Dr. Holger Gerhardt
  Vascular Biology, Cancer Research
  Lincolns Inn Fields laboratory
  44 Lincoln's Inn Fields
  London, WC2A 3PX
  UK
  Holger.Gerhardt@cancer.org.uk
  
  
  Dr. Richard Goldstein
  Div. of Mathematical Biology
  National Institute for Medical Research
  The Ridgeway, Mill Hill
  London NW7 1AA, U.K.
  rgoldst@nimr.mrc.ac.uk
  
  
  Prof. Felix M. Goni
  Universidad del Pais Vasco
  Unidad de Biofisica (CSIC-UPV/EHU)
  E-48080 Bilbao, Spain
  felix.goni@ehu.es
  
  
  Dr. Helen C. Hailes
  Reader in Chemical Biology,
  Department of Chemistry
  University College London 
  20 Gordon Street,
  London WC1H 0AJ, UK
  h.c.hailes@ucl.ac.uk
  
  
  Per Hammarstrom, PhD
  Professor of Protein Chemistry
  IFM-Department of Chemistry
  Linkoping University, Sweden
  perha@ifm.liu.se
  
  
  Prof. Michael Kozlov
  Department of Physiology-Pharmacology
  Faculty of Medicina
  Tel Aviv University
  Ramat Aviv, Israel
  michk@post.tau.ac.il
  
  
  Prof. Richard Lin
  Richard Lin, M.D.
  Associate Professor of Medicine
  Division of Hematology
  Stony Brook University
  Stony Brook, NY 11794-8661, USA
  rzlin@notes.cc.sunysb.edu
  
  
  Dr. R. Marquez
  Ian Sword Lecturer of Bioorganic Chemistry
  WestCHEM, Department of Chemistry
  University of Glasgow,
  Glasgow, G12 8QQ, UK
  rudim@chem.gla.ac.uk
  
  
  Dr. Lorenz Mayr
  Unit Head Biology, Protease Platform
  Novartis Pharma AG / NIBR
  Fabrikstrasse 16.3.43
  CH-4002 Basel, Switzerland
  lorenz.mayr@novartis.com
  
  
  Dr. Rob van Montfort 
  Team Leader Structure-Based Drug Design 
  Sections of Cancer Therapeutics and Structural Biology 
  The Institute of Cancer Research 
  15 Cotswold Road 
  Sutton SM2 5NG, UK 
  rob.vanmontfort@icr.ac.uk
  
  
  Prof. William S. Price
  Nanoscale Organisation and Dynamics Group
  College of Health and Science 
  Campbelltown Campus - Building 21.G.45 
  University of Western Sydney 
  Locked Bag 1797 
  Penrith South DC NSW 1797, Australia
  w.price@uws.edu.au
  
  
  PD Dr. Heino Prinz
  Biochemical Analytic
  Max-Planck-Institute for molecular Physiology
  Otto-Hahn-Str. 11
  44227 Dortmund, Germany
  heino.prinz@mpi-dortmund.mpg.de
  
  
  Dr. Alfred A. Rabow
  AstraZeneca, Mereside
  Dept. Computational and
  Physical Chemistry
  Alderley Park
  Cheshire SK10 4TG, UK
  Al.Rabow@astrazeneca.com
  
  
  Dr. Alan J. Schafer, PhD 
  Head of Science Funding
  The Wellcome Trust 
  215 Euston Road 
  London NW1 2BE, UK
  a.schafer@wellcome.ac.uk
  
  
  Dr. Edward Tate 
  B.Sc. (Dunelm), Ph.D. (Cantab) 
  BBSRC David Phillips Research Fellow 
  Department of Chemistry  
  Imperial College London 
  Exhibition Rd. 
  London SW7 2AZ, UK
  e.tate@imperial.ac.uk
  
  
  Dr. Ramon Vilar 
  Reader in Inorganic Chemistry 
  Department of Chemistry 
  Imperial College London 
  South Kensington 
  London SW7 2AZ , UK
  r.vilar@imperial.ac.uk
  
  
  Prof. Christopher A. Voigt
  Byer's Hall MC 2540, Room 408C
  1700 4th Street
  San Francisco, CA 94158-2330, USA
  cavoigt@picasso.ucsf.edu
  
  
  Dr Barrie Wilkinson FRSC 
  Director 
  Natural Products Chemistry 
  Biotica 
  Chesterford Research Park 
  Little Chesterford 
  Essex CB10 1XL, UK
  barrie.wilkinson@biotica.com
  
  
  Prof. Patrick Williamson
  Edward S. Harkness Professor of Biology
  Biology Department
  Amherst College, 
  Amherst, MA 01002, USA 
  plwilliamson@amherst.edu
  
  

• Guide to authors

  Manuscript Submission
  
  
  Submission of a manuscript implies: that the work described has not been published before; that it is not under consideration for publication anywhere else; that its publication has been approved by all co-authors, if any, as well as by the responsible authorities – tacitly or explicitly – at the institute where the work has been carried out. The publisher will not be held legally responsible should there be any claims for compensation.
  
  
  Permissions
  
  
  Authors wishing to include figures, tables, or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) for both the print and online format and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors.
  
  
  Online Submission
  
  
  Authors should submit their manuscripts online. Electronic submission substantially reduces the editorial processing and reviewing times and shortens overall publication times. Please follow the hyperlink “Submit online” on the right and upload all of your manuscript files following the instructions given on the screen.
  
  
  Title Page
  
  
  The title page should include:
  The name(s) of the author(s)
  A concise and informative title
  The affiliation(s) and address(es) of the author(s)
  The e-mail address, telephone and fax numbers of the corresponding author
  
  
  Abstract
  
  
  Please provide an abstract of 150 to 250 words. The abstract should not contain any undefined abbreviations or unspecified references.
  
  
  Keywords
  
  
  Please provide 4 to 6 keywords which can be used for indexing purposes.
  
  
  Text Formatting
  
  
  Manuscripts should be submitted in Word.
  Use a normal, plain font (e.g., 10-point Times Roman) for text.
  Use italics for emphasis.
  Use the automatic page numbering function to number the pages.
  Do not use field functions.
  Use tab stops or other commands for indents, not the space bar.
  Use the table function, not spreadsheets, to make tables.
  Use the equation editor or MathType for equations.
  Note: If you use Word 2007, do not create the equations with the default equation editor but use the Microsoft equation editor or MathType instead.
  Save your file in doc format. Do not submit docx files.
  
  
  Manuscripts with mathematical content can also be submitted in LaTeX.
  
  
  Headings
  
  
  Please use no more than three levels of displayed headings.
  
  
  Abbreviations
  
  
  Abbreviations should be defined at first mention and used consistently thereafter.
  
  
  Footnotes
  
  
  Footnotes can be used to give additional information, which may include the citation of a reference included in the reference list. They should not consist solely of a reference citation, and they should never include the bibliographic details of a reference. They should also not contain any figures or tables.
  Footnotes to the text are numbered consecutively; those to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data). Footnotes to the title or the authors of the article are not given reference symbols.
  Always use footnotes instead of endnotes.
  
  
  Acknowledgments
  
  
  Acknowledgments of people, grants, funds, etc. should be placed in a separate section before the reference list. The names of funding organizations should be written in full.
  
  
  Scientific style
  
  
  Please always use internationally accepted signs and symbols for units (SI units).
  Nomenclature: Insofar as possible, authors should use systematic names similar to those used by Chemical Abstract Service or IUPAC.
  
  
  Genus and species names should be in italics.
  
  
  Generic names of drugs and pesticides are preferred; if trade names are used, the generic name should be given at first mention.
  
  
  Please use the standard mathematical notation for formulae, symbols, etc.:
  Italic for single letters that denote mathematical constants, variables, and unknown quantities
  
  
  Roman/upright for numerals, operators, and punctuation, and commonly defined functions or abbreviations, e.g., cos, det, e or exp, lim, log, max, min, sin, tan, d (for derivative)
  
  
  Bold for vectors, tensors, and matrices.
  
  
  References
  
  
  Citation
  
  
  Cite references in the text by name and year in parentheses. Some examples:
  - Negotiation research spans many disciplines (Thompson 1990).
  - This result was later contradicted by Becker and Seligman (1996).
  - This effect has been widely studied (Abbott 1991; Barakat et al. 1995; Kelso and Smith 1998; Medvec et al. 1993).
  
  
  Reference list
  
  
  The list of references should only include works that are cited in the text and that have been published or accepted for publication. Personal communications and unpublished works should only be mentioned in the text. Do not use footnotes or endnotes as a substitute for a reference list.
  
  
  Reference list entries should be alphabetized by the last names of the first author of each work.
  
  
  Journal article
  
  
  Nugen S, Baeumner HJ (2008) Trends and opportunities in food pathogen detection. Anal Bioanal Chem 391:451-454
  or
  Nugen S, Baeumner HJ (2008) Anal Bioanal Chem 391:451-454
  
  
  Article by DOI
  
  
  Slifka MK, Whitton JL (2000) Clinical implications of dysregulated cytokine production. J Mol Med. Doi:10.1007/s001090000086
  
  
  Book
  
  
  South J, Blass B (2001) The future of modern genomics. Blackwell, London
  
  
  Book chapter
  
  
  Brown B, Aaron M (2001) In: Smith J (ed) The rise of modern genomics, 3rd edn. Wiley, New York
  
  
  Online document
  
  
  Healthwise Knowledgebase (1998) US Pharmacopeia, Rockville. http://www.healthwise.org. Accessed 21 Sept 1998
  
  
  Always use the standard abbreviation of a journal’s name according to the ISSN List of Title Word Abbreviations, see www.issn.org/2-22661-LTWA-online.php
  
  
  For authors using EndNote, Springer provides an output style that supports the formatting of in-text citations and reference list.
  
  
  Tables
  
  
  All tables are to be numbered using Arabic numerals.
  Tables should always be cited in text in consecutive numerical order.
  For each table, please supply a table caption (title) explaining the components of the table.
  
  
  Identify any previously published material by giving the original source in the form of a reference at the end of the table caption.
  Footnotes to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data) and included beneath the table body.

• Contact

  Springer-Verlag
  Planung Chemie
  Marion Hertel
  
  
  Tiergartenstraße 17 
  69121 Heidelberg 
  Germany
  
  
  E-mail: marion.hertel@springer.com