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Volume 12
Issue 3
Online publication date 2012-07-27
Title Central nervous system hypoxic-ischemic injuries in newborns and infants: Initiation of membrane destructive process
Author Gulomjan Khalimbetov
Abstract Comparison of S100 protein and MDA concentrations in blood of newborns and infants with hypoxic-ischemic encephalopathy demonstrated difference in the parameters by a type of cerebral ischemic syndrome. Follow-up study of serum S100 protein concentrations demonstrated absence of normalization in the parameter in patients with psychomotor retardation and paroxysmal syndrome, no normalization of MDA level found in examinees with emotional and behavioral disorders and psychomotor retardation.
Barashneva, Yu., 2001. Perinatal neurology [Perinatalnaya Nevrologiya], in Russian, Moscow: Triada-x Publishing house

Bulakhova, S. and Belikova, D., 2007. “Treatment of perinatal nervous system injuries in infants, pharmaco-therapeutic effect of hopantenic acid,” Pediatrics [Pediatriya], in Russian, Vol.09, No.1, pp.19-21 

Golosnaya, G., Petrukhin, A., Markevich, K., Trifonova, O., 2004. “Changes in S100 protein in newborns with perinatal CNS hypoxic injury,” Pediatrics [Pediatriya], in Russian, No.1, pp.10-15

Khalimbetov, G., 2011. “Diagnostic significance of evaluation of neuropeptides in newborns with perinatal central nervous system hypoxia,” Neurology [Nevrologija], in Russian, No.3, pp.21-24

Nagoev, B. and Tulupova, M., 2008. “Study on prooxidant properties of blood plasma in patients with psoriasis by malondialdehyde level,” Clinical laboratory diagnosis [Klinicheskaya laboratornaya diagnostika], in Russian, No.8, pp.15-17

Pekny, M., Jonasson, C., Eliasson, C. et al., 1999. “Abnormal reaction to central nervous system injury  in mice lacking glial fibrillary acidic protein and vimentin,” J. Cell Biol., Vol.145, No.3, pp.503-14  

Shamansurov, Sh., Sokhieva, N., Uzakova, Ch., 2010. “Clinical-anamnestic peculiarities of consequences of perinatal injury of nervous system in rural infants,” Neurology [Nevrologiya], in Russian, No.2(46), pp.23-25

Soatov, T., Ibragimov, U., Khaibullina, Z., 2009. Lipid peroxidation in biological membranes Tashkent Medical Pediatric Institute Printing House [Biologik sistemalarda kislorodning erkin radikallarining tasiri va himoya mehanizmlari], in Uzbek

Volodin, N., Medvedev, M., Rogatkin, S., 2001. “Perinatal encephalopathy and its complications, aspects of semiotics, early diagnosis and treatment,” Russian Pediatric Journal [Rossijskij Pediatricheskij Zhurnal], in Russian, No.1, pp.4-8

Yaremenko, B., Yaremenko, A., Goryainova, T., 2002. Minimal cerebral dysfunctions in infants [Minimalnye disfunkstii golovnogo mozga u detey], in Russian, St. Petersburg: Salit - Medkniga Publishing House

Keywords Сentral nervous system (CNS), hypoxic-ischemic injuries, membrane destruction.
Pages 16-19
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