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Volume 12
Issue 3
Online publication date 2012-07-27
Title Effect of HGV-infection on clinical course of hepatitis C and the possible role of endogenous interferon
Author Aizhan Dzhumagalieva, Idelbay Shuratov, Maria Omarova, Lyazat Orakbay, Daniyar Aspetov
Abstract Light form of disease flow was observed in 69.3% (9/13) among the patients with acute hepatitis C, and in 77.8% (7/9) among the patients with non verified hepatitis. Detectability of RNA-HGV consists of 77.8% (7/9) and 42.8% (3/7) correspondingly among the patients’ groups with light form of disease. All HGV RNA positive patients had 2 times lower content of total bilirubin and ALT in the blood comparing to RNA-HGV negative patients. HGV showed an active (4.7 EA) ability to induce the interferon formation. The C G hepatitis patients had interferon titer equal to 3.7 EA, which apparently provides relief of hepatitis C clinical picture.
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Keywords C-hepatitis, clinical course, co-infection, HCV HGV, induction of interferon HGV
Pages 40-43
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