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Volume 13
Issue 4
Online publication date 2012-12-15
Title Association of rs738409 PNPLA3 with the development of nonalcoholic fatty liver disease in patients of Uzbek nationality
Author Guzal Sobirova
Abstract The results of study of 53 patients with NAFLD were presented in the article. It was revealed the association of SNPs in the gene PNPLA3 rs738409 with the development of NAFLD in patients of Uzbek nationality. It also provides reliable pathogenetic link the risk allele G with the progression of NAFLD. For patients with NAFLD and G allele is usefully to addition pentoxifylline on the background of the basic therapy.
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Keywords Non-alcoholic fatty liver disease, gene polymorphism, metabolites of nitrogen oxide
Pages 41-44
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