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Volume 3
Issue 3
Online publication date 2010-09-15
Title Influence of glycorazmulin on the parameters of carbohydrate metabolism in alloxane diabetes
Author Ziyoda Fayzieva, Ziyovutdin Khakimov
Abstract There was studied effect of glycorazmulin on the morphological structure of the liver and pancreatic gland under the conditions of alloxane diabetes. The study found that that glycorazmulin eliminates pathomorphological changes that occur in alloxane diabetes in the liver and pancreatic gland, and stimulates reparative processes in these organs. The effect of this preparation is mainly directed to stimulation of the regeneration of β-cells. The elimination of histostructural changes resulted in compensation of the damaged metabolic processes in diabetes mellitus. Besides, marked increase in C-peptide in the blood is the confirmation of the insulin secretion stimulation under the effect of this preparation.
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References
Atkinson, M., 2000. Atlas of diabetes. pp.45-57

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Charles, M., Clark, H., 1998. “Oral therapy in type 2 diabetes: Pharmacological properties and clinical use of currently available agents,” Diabetes spectrum, Vol.11, No4, pp.211-21

Faizieva, Z., Aliev, Kh., 2003. “Influence of glukozamin on blood sugar concentration in experimental pathology,” Collection of works, 3nd Congress of Russian Pharmacologists Scientific Society: Essential issues in pharmacology, Moscow, pp.245

Kurkin, V., Zapesochnaya, G., Avdeeva, E. et al., 1995. “Phytochemical investigation of medicinal plants genera Rhodiola, poplar, willow, rostoropsha, dandelion, containing flavonoids,” Contemporary aspects in studying medical plants, Moscow, pp.151-57

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Maslov, L., Lishmanov, Yu., 2007. “Cardioprotective and antiarrhythmic properties of Rhodiolae roseae preparations,” Experimental and Clinicl Pharmacology, Vol.70, No5, pp.59-67

Keywords Glycorazmulin, alloxane diabetes, liver, pancreatic gland, islets of Langerhans.
DOI http://dx.doi.org/10.15208/mhsj.2010.36
Pages 5-8
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