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Volume 3
Issue 3
Online publication date 2010-09-15
Title Method of computer esthesiometry on distal parts of the lower extremities in diagnostics of Charcot-Marie-Tooth disease
Author Natalia Shnayder, Elena Glushchenko, Diana Dmitrenko, Ekaterina Kozulina, Elena Kantimirova, Olga Darsavelidze, Ilya Kiselev, Marina Pilugina
Abstract

The paper discusses using a computer esthesiometry method in diagnostics of hereditary neuropathy with primary defeat of myelinic covers of lower extremities peripheral nerves. Vibration sensitivity in lower extremities was examined using computer diagnostic equipment “Vibrotester - MBN” in a wide range of vibration frequencies (8, 16, 32, 63, 125, 250, 500 Hz). Statistical data processing of research was performed with the program Statistica v.7.0 (StatSoft, USA). The reference corridors of vibration sensitivity in lower extremities for persons of young and middle age are compared with those at patients with Charcot-Marie-Tooth disease (CMT). Statistically significant increase of vibration sensitivity thresholds in a wide range of vibration frequencies and in comparison  with healthy volunteers is shown. Computer esthesiometry method demonstrates high sensitivity in diagnostics of hereditary neuropathy with primary defeat of myelinic covers of lower extremities peripheral nerves

Citation
References
Glushenko, E., 2009. “Diagnostic of Charcot-Marie-Tooth hereditary neuropathy in children,” Materials of the Third Siberian Congress “Human and Medicine”, Vol.1, pp.62-66

Glushenko, E., Kantimirova, E., Kozulina, E., Volkov, S., Shnayder, N., 2009. “The interdisciplinary approach to diagnostics of neuropathies’ mixed forms in closed administrative-territorial region Zheleznogorsk, Krasnoyarsk Region,” Vestnik of Clinical Hospital No51 (RF), Vol.3, No5, pp.52-55

Kantimirova, L., Trikman, O., Kantimirova, E., Glushenko, E., Shnayder, N., 2008, “Clinical and epidemiological characteristic of polyneuropathies in closed administrative-territorial region Zheleznogorsk, Krasnoyarsk Region,” Bulletin of Clinical Hospital No.51 (RF), Vol.3, No5, pp.31-34

Kirichkova, G., Shnayder, N., Petrova, M. et al., 2009. “Parameters of computer pallesthesiometria in healthy volunteers,” The Functional diagnostic (RF), No1, pp.68-72

Kirichkova, G., Ustinovich, M., Shnayder et al., 2008. “The improved method of pallesthesia examination on lower extremities of polyneuropathy with different genesis with original stand,” Materials of the Forum of Innovative Technologies-2020, pp.150-51

Shnayder, N., Kirichkova, G., Kozulina, E., 2008. “Charcot-Marie-Tooth hereditary neuropathy: capabilities of functional diagnostics,” The Functional diagnostics (RF), No3, pp.85-90

Shnayder, N., Glushenko, E., Kantimirova, E., Kozulina, E., 2009a. “Hereditary neuropathy: epidemiology, classification, and disease’s features,” Bulletin of Novosibirsk State University, Ser.: Biology, clinical medicine, Vol.7, No4, pp.152-59

Shnayder, N., Kantimirova, E., Glushenko, E., Kozulina, E., 2009b. “The epidemiology of peripheral neuropathy in Russian Federation and foreign countries,” Bulletin of Novosibirsk State University, Ser.: Biology, clinical medicine, Vol.7, No3, pp.139-42

Shnayder, N., Petrova, M., Kirichkova, G., Kurumchina, O., 2009c. “Algorithm of diabetic neuropathy diagnostics (tutorial for practical physicians’ postgraduate education),” RF, Krasnoyarsk, p.185

Keywords Vibration sensitivity, computer esthesiometry, Charcot-Marie-Tooth disease (CMT).
DOI http://dx.doi.org/10.15208/mhsj.2010.39
Pages 20-24
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