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Volume 5
Issue 1
Online publication date 2011-03-01
Title The condition of hemato and liquor-encephalic barriers of the human brain in acute blood loss on the background of alcoholemia and drug intoxication
Author Said Indiaminov
Abstract By means of the histological methods, scanning and transmission electronic microscopy the cerebral cortex of the brain (field 6), the walls of III and IV ventricles of the brain of dead people, who had died of acute anemia on the background of alcohol intoxication and drug intoxication, have been studied.  Examination has found thinning of the basal membrane of capillaries, development of fissures in the places of contact of neighboring endothelial cells, also between basal membrane and endothelial cells, and swelling of pericytes. In the wall of brain ventricles, a marked polymorphism of the ependymal cells and disturbance of the continuity of the layer are noted. Accumulation of blood cells, thickening of detritus, crystal structures are seen on ependymal surface. Reported symptoms reflect the disturbance of permeability of hematoencephalic and liquor-encephalic barriers of the brain with a combination of traumatic blood loss with alcohol and drug intoxication.
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Keywords Brain, blood loss, alcohol intoxication, drug intoxication
Pages 30-34
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