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Volume 8
Issue 4
Online publication date 2011-07-29
Title Cytomegalovirus infection in pregnancy and the fetus: A case presentation
Author Aziza Khodjaeva
Abstract The objective of this case study was to study possible clinical manifestations of Human Cytomegalovirus (HCMV) which demonstrate the vertical transmission of HCMV from mother to her children.  The patient, an HCMV infected woman with chronic socioeconomic problems and depression, was observed between 2003 and 2011. During that time, five pregnancies were clinically monitored with use of immunograms, PCR, and general blood and urine analyses. This case showed that HCMV infection of pregnant mother caused death of newborns due to HCMV-associated complications. Due to combinatory therapy the fifth pregnancy was successful with delivery of a HCMV asymptomatic newborn. With the deficit of knowledge on HCMV and its effect on pregnant women in Uzbekistan, such research for the clinical manifestation of the virus is vital to deter the transmission of the virus and improve the wellbeing of both mother and child.
American Academy of Pediatrics. Cytomegalovirus Infection. In: Pickering LK, Baker CJ, Kimberlin DW, Long SS (Eds.), Red Book: 2009 Report of the Committee on Infectious Diseases. 28th ed.,  Elk Grove Village, IL: American Academy of Pediatrics, pp.276-77

Andrewes, C, 1967. The natural history of viruses, London, Weidenfeld and Nicholson
Farber, N., 1989. “Cytomegalovirus infection in clinical medicine,” Ter. Akhiv [Citomegalovirusnaya infekciya v klinicheskoi medicine], in Russian, pp.6-11

Granitov, V., 2001. Herpes virus infections [Gerpesvirusnue infekcii], in Russian, Moscow: Medicine Book

Kazantsev, A., Popova, N., 1980. “Intrauterine infectious diseases in children and their profilaxis” [Vnutriutrobnue infekcionnue zabolevaniya u detei i ih profilactica], in Russian, Medicine

Volodin, N. et al., 2001. Protocols for diagnosis, treatment and prophylaxis of intrauterine infections in newborns, Moscow: GOU VUNMTs Ministry of Health of the Russian Federation

Keywords Infection, cytomegalovirus, prenatal infection, social conditions, herpes viruses, treatment of herpes viruses
Pages 27-31
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