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Volume 9
Issue 5
Online publication date 2011-11-05
Title Sensitivity of сomputer esthesiometry on distal parts of the upper extremities at patients with hereditary neuropathy Сharcot-Marie-Tooth
Author Natalia Shnayder, Elena Glushchenko, Elena Kantimirova, Diana Dmitrenko, Ekaterina Kozulina, Vladimir Maksimov
Abstract The purpose - to define the diagnostic importance of computer esthesiometry for use in diagnostics of hereditary neuropathy with primary defeat of myelin sheath of peripheral nerves of the upper extremities. Materials and methods: 47 individuals in a condition of relative health (control group) from 21 to 50 years, comparable group - 40 patients from 6 to 81 years, with hereditary neuropathy Charcot-Marie-Tooth (CMT). Vibrating sensitivity investigated by means of computer vibrometer «Vibrotester MBN» VТ-02-1 (MBN, RF) in a wide strip of frequencies of vibration (8, 16, 32, 64, 125, 250, 500 Hz). Statistical data processing of research is lead by means of programs STATISTICA v. 7.0 (StatSoft, USA). Results and discussion: We compared received corridors vibrating sensitivity on the upper extremities for healthy volunteers with those at patients with CMT. Statistically significant increase of vibration sensitivity thresholds in a wide range of vibration frequencies on upper extremities and at patients with CMT versus healthy volunteers is shown. Computer esthesiometry method demonstrates high sensitivity in diagnostics of hereditary neuropathy with primary damage of myelin sheath of peripheral nerves of upper extremities on an example of CMT.
Auer-Grumbach, M., Wagner, K., Strasser-Fuchs, S. et al., 2000 “Clinical predominance of proximal upper limb weakness in CMT1A syndrome,” Muscle Nerve., Vol.23, No.8, pp.1243-249

Benstead, T., Grant, I., 2001. “Progress in clinical neurosciences: Charcot-Marie-Tooth disease and related inherited peripheral neuropathies,” Can. J. Neurol. Sci., Vol.28, No.3, pp.199-214

Kirichkova, G., Ustinovich, M., Shnayder, N., Petrova, M., Kurumchina, O., 2008. “The improved method of pallesthesia examination on lower extremities of polyneuropathy with different genesis with original stand”, Materials of the Forum of Innovative Technologies [Materiali Foruma Innovatcionnikh tekhnologii], in Russian, pp.150-51

Shnayder, N., Kirichkova, G., Kozulina, E., 2008. “Charcot-Marie-Tooth hereditary neuropathy: Capabilities of functional diagnostics,” The Functional diagnostics [Funkctionalnaya diagnostika], in Russian, Vol.3, pp.85-90

Shnayder, N., Kozulina, E., Glushenko, E., Kantimirova, E., 2010 Hereditary neuropathy Charcot-Marie-Tooth: A Tutorial for postgraduate education of doctors, Krasnoyarsk Publisher Grotesque, in Russian

Shnayder, N., Gluschenko, E., Dmitrenko, D., Kozulina, E., Kantimirova, E., Darsavelidze, O., Kiselev, I., Pilugina, M., 2010. “Method of computer esthesiometry on distal parts of the lower extremities in diagnostics of Charcot-Marie-Tooth disease,” Medical and Health Science Journal, Vol.3, pp.20-24

Keywords Vibration perception, computer esthesiometry, hereditary neuropathy Charcot-Marie-Tooth (CMT)
Pages 25-30
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